3-amino-3-hydroxypropanoic acid 9H-fluoren-9-ylmethyl ester
N-fmoc-ethanolamine
CAS: 105496-31-9
Molecular Formula: C17H17NO3
3-amino-3-hydroxypropanoic acid 9H-fluoren-9-ylmethyl ester - Names and Identifiers
| Name | N-fmoc-ethanolamine |
| Synonyms | Fmoc-L-GLY-OL Fmoc-Glycinol N-Fmoc-glycinol N-fmoc-ethanolamine 2-(Fmoc-amino)ethanol 2-(FMOC-AMINO)-ETHANOL N-(9-fluorenylmethoxycarbonyl)ethanol-amine 9H-fluoren-9-ylmethyl (2-hydroxyethyl)carbamate 9H-fluoren-9-ylmethyl N-(2-hydroxyethyl)carbamate (2-HYDROXY-ETHYL)-CARBAMIC ACID 9H-FLUOREN-9-YLMETHYL ESTER 3-amino-3-hydroxypropanoic acid 9H-fluoren-9-ylmethyl ester |
| CAS | 105496-31-9 |
| EINECS | 626-390-8 |
| InChI | InChI=1/C17H17NO3/c19-10-9-18-17(20)21-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16,19H,9-11H2,(H,18,20) |
3-amino-3-hydroxypropanoic acid 9H-fluoren-9-ylmethyl ester - Physico-chemical Properties
| Molecular Formula | C17H17NO3 |
| Molar Mass | 283.32 |
| Density | 1.238±0.06 g/cm3(Predicted) |
| Melting Point | 144-147 °C (lit.) |
| Boling Point | 502.7±33.0 °C(Predicted) |
| Flash Point | 257.8°C |
| Solubility | DMSO, Methanol |
| Vapor Presure | 6.34E-11mmHg at 25°C |
| Appearance | White powder |
| Color | White |
| pKa | 11.38±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.609 |
| MDL | MFCD00235927 |
3-amino-3-hydroxypropanoic acid 9H-fluoren-9-ylmethyl ester - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29242990 |
3-amino-3-hydroxypropanoic acid 9H-fluoren-9-ylmethyl ester - Introduction
2-(N-fluorenylmethoxycarbonylamino) ethanol is an organic compound with the chemical formula C11H15NO3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
2-(N-fluorenylmethoxycarbonylamino) ethanol is a solid crystalline white powder, soluble in organic solvents such as alcohols, ethers and ketones, but insoluble in water. It has the ammonia aroma of aromatic amino compounds and has strong reducibility.
Use:
2-(N-fluorenylmethoxycarbonylamino) ethanol is commonly used in organic synthesis reactions as a reducing agent and a protecting group. It can be reduced to the corresponding aromatic amines, and can also be hydroxylated by sodium cyanide to produce the corresponding alcohol compounds. In addition, it can also be used as an intermediate in the field of dyes and pharmaceuticals.
Preparation Method:
2-(N-fluorenylmethoxycarbonylamino) ethanol can be prepared by the following steps:
1. fluorene methyl chloroformate reacts with amino acid to obtain fluorene methyl carbamate.
2. reacting the obtained fluorenylcarbamate with ethanol, deacidification and deprotection to obtain 2-(N-fluorenylmethoxycarbonylamino) ethanol.
Safety Information:
2-(N-fluorenylmethoxycarbonylamino) ethanol is a relatively safe compound in general. However, as an organic compound, it needs to comply with corresponding safety measures when using and handling. For example, contact with skin, eyes and respiratory tract should be avoided, and appropriate personal protective equipment should be used during the operation.
Nature:
2-(N-fluorenylmethoxycarbonylamino) ethanol is a solid crystalline white powder, soluble in organic solvents such as alcohols, ethers and ketones, but insoluble in water. It has the ammonia aroma of aromatic amino compounds and has strong reducibility.
Use:
2-(N-fluorenylmethoxycarbonylamino) ethanol is commonly used in organic synthesis reactions as a reducing agent and a protecting group. It can be reduced to the corresponding aromatic amines, and can also be hydroxylated by sodium cyanide to produce the corresponding alcohol compounds. In addition, it can also be used as an intermediate in the field of dyes and pharmaceuticals.
Preparation Method:
2-(N-fluorenylmethoxycarbonylamino) ethanol can be prepared by the following steps:
1. fluorene methyl chloroformate reacts with amino acid to obtain fluorene methyl carbamate.
2. reacting the obtained fluorenylcarbamate with ethanol, deacidification and deprotection to obtain 2-(N-fluorenylmethoxycarbonylamino) ethanol.
Safety Information:
2-(N-fluorenylmethoxycarbonylamino) ethanol is a relatively safe compound in general. However, as an organic compound, it needs to comply with corresponding safety measures when using and handling. For example, contact with skin, eyes and respiratory tract should be avoided, and appropriate personal protective equipment should be used during the operation.
Last Update：2024-04-09 20:45:29
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Product Name: Fmoc-Glycinol Visit Supplier Webpage Request for quotationCAS: 105496-31-9
Tel: 18301782025
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Mobile: 18021002903
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